Hormone Therapy and Breast Cancer Incidence Data


This hormone therapy and breast cancer incidence dataset may be useful to people interested in exploring the relationship between postmenopausal hormone therapy and breast cancer incidence. The dataset includes information from 603,411 screening mammograms performed on women in the Breast Cancer Surveillance Consortium from January 1997 to December 2003. Results of an analysis of these data were published by Kerlikowske et al. in the September 2007 issue of the Journal of the National Cancer Institute. This dataset includes screening mammograms in women aged 50-69 who did not have a previous diagnosis of breast cancer and who had undergone breast mammography in the prior 9 to 30 months. The mammogram data were linked to cancer registry and pathology data to identify incident breast cancer (invasive or ductal carcinoma in situ) within one year after the screening mammogram. This aggregate dataset includes frequencies and adjusted quarterly rates of postmenopausal hormone therapy use and breast cancer (overall and by invasive/DCIS and estrogen receptor status). All rates were adjusted for age, BCSC mammography registry, and time since the previous mammogram. Investigators may wish to explore alternative methods of analyzing the data and evaluating trends. Invasive cancers were categorized by estrogen receptor status as positive, negative, or unknown/not done.


Acknowledge the BCSC

The following must be cited when reproducing this data:

"The Breast Cancer Surveillance Consortium and its data collection and sharing activities are funded by the National Cancer Institute (P01CA154292). Downloaded xx/xx/xxxx from the Breast Cancer Surveillance Consortium Web site - http://www.bcsc-research.org/."

Please acknowledge the BCSC:

“We thank the participating women, mammography facilities, and radiologists for the data they have provided. You can learn more about the BCSC at: http://www.bcsc-research.org/."

Information about the BCSC may also be included in the methods section using language such as:

"Data for this study was obtained from the BCSC: http://www.bcsc-research.org/."

Please cite the publication that used this dataset:

Kerlikowske K, Miglioretti DL, Buist DS, Walker R, Carney PA; National Cancer Institute-Sponsored Breast Cancer Surveillance Consortium. Declines in invasive breast cancer and use of postmenopausal hormone therapy in a screening mammography population. J Natl Cancer Inst. 2007 Sep 5;99(17):1335-9. doi: 10.1093/jnci/djm111. Erratum in: J Natl Cancer Inst. 2007 Oct 3;99(19):1493. PMID: 17698950.



Investigators can access this dataset by submitting the information below.

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